endocrine disorders


Disturbances of the function of the ductless glands that may be metabolic in origin and may be associated with or aggravated by emotional factors, producing mental and behavioral disturbances in addition to physical signs

Of particular significance in psychiatry is the hypothalamic-pituitary-adrenal (HPA) axis, consisting of a self-regulatingcircle of neurohormones released from the hypothalamus and stimulating the release of hormones from the anterior pituitary.  These in thru stimulate hormone secretion in target organs (thyroid, adrenal, and gonads).  The HPA axis is involved in the regulation of sexual activity, thirst and hunger behaviors, sleep, learning and memory, and perhaps in antidepressant activity.

Source: Edgerton, Jane E. 1994. American Psychiatric Glossary, 7th Edition. Washington, DC: American Psychiatric Press











   

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