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An abnormal DNA sequence that is associated with the presence of or vulnerability to a disease. More often than not, the abnormality is not the gene actually responsible for the disorder, but a DNA segment that remains physically close to the responsible gene and thus signals the presence of that gene. Huntington's disease is an example of the effects of the gene. Source: Edgerton, Jane E. 1994. American Psychiatric Glossary, 7th Edition. Washington, DC: American Psychiatric Press
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