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(chorea) A rare hereditary and progressive degenerative disease of the central nervous
system transmitted as an autosomal dominant trait. Onset is typically in
middle adult life with involuntary movements of the face, hands, and shoulders.
These movements become more pronounced and often result in a massive jerkiness
of the limbs, facial muscles, and diaphragm. Progressive dementia
typically parallels the movement disorder and the person is incapable of doing
anything. Psychosis may develop, most commonly depression that varies in
degree (ill-sustained).
Source: Edgerton, Jane E. 1994. American Psychiatric Glossary, 7th Edition. Washington, DC: American Psychiatric Press
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