Hemophilia

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  • a disease, usually hereditary, that produces a tendency toward excessive bleeding from even slight wounds
    Source: Noland, George B. 1983. General Biology, 11th Edition. St. Louis, MO. C. V. Mosby
  • An X-linked recessive genetic disease, caused by a mutation in the gene for clotting factor VIII (hemophilia A) or clotting factor IX (hemophilia B), which leads to abnormal blood clotting.
  • Hemophilia is an inherited disease, most commonly affecting males, that is characterized by a deficiency in blood clotting. The responsible gene is located on the X chromosome, and since males inherit only one copy of the X chromosome, if that chromosome carries the mutated gene then they will have the disease. Females have a second, usually normal, copy of the gene on their other X chromosome, so they capable of passing on the disease without experiencing its symptoms.


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