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  • a type of basic protein associated with DNA in chromosomes
    Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row
  • A histone is a protein that provides structural support to a chromosome. In order for very long DNA molecules to fit into the cell nucleus, they wrap around complexes of histone proteins, giving the chromosome a more compact shape. Some variants of histones are associated with the regulation of gene expression.

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