Nucleosome

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  • the basic unit of eukaryotic chromosome structure; composed of DNA and histone subunits
    Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row
  • A nucleosome is the basic repeating unit of eukaryotic chromatin. In a human cell, about six feet of DNA must be packaged into a nucleus with a diameter less than a human hair. A single nucleosome consists of about 150 base pairs of DNA sequence wrapped around a core of histone proteins. The nucleosomes are arranged like beads on a string. They are repeatedly folded in on themselves to form a chromosome.


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