Promoter

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  • the region upstream of a gene to which RNA polymerase binds
    Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row
  • A region of DNA extending 150-300 bp upstream from the transcription start site that contains binding sites for RNA polymerase and a number of proteins that regulate the rate of transcription of the adjacent gene.
  • A promoter is a sequence of DNA needed to turn a gene on or off. The process of transcription is initiated at the promoter. Usually found near the beginning of a gene, the promoter has a binding site for the enzyme used to make a messenger RNA (mRNA) molecule.


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